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Invoeringen toepassingvan CAS-nr.941685-27-4|4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,{{10} }d]pyrimidine
4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,{{9} }d]pyrimidine is een belangrijk tussenproduct bij de bereiding van de januskinaseremmer INCB018424.
Synoniemen:
trimethyl-[2-[[4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidine-7-yl]methoxy]ethyl]silaan ;
Specificatie van CAS-nr.941685-27-4|4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,{{10} }d]pyrimidine
|
ITEMS |
SPECIFICATIE |
|
CAS |
941685-27-4 |
|
MF |
C15H21N5OSi |
|
Mw |
315.45 |
|
Dikte |
1,20±0,1 g/cm3 (voorspeld) |
|
Kookpunt |
501,8±50,0 graden (voorspeld) |
|
zuurgraadcoëfficiënt (pKa) |
10.87±0.50(Voorspeld) |
Paktie en transportvan Introductie en toepassing vanCAS-nr.941685-27-4|4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,{{10} }d]pyrimidine
Pakket:0.1g,1g,5g,25g,100g,500g,1kg
Transport: per koerier/door de lucht/over zee
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Werkwijze voor de bereiding van kristalmodificatie 3 van (R)-3-(4-(7H-pyrrolo [2, 3 d] pyrimidine-4-yl)-1H-pyrazol{ {10}}yl)-3-cyclopentylpropaannitrilhydrochloride
ST Rajan, S Eswaraiah, VT Mathad, SV Narasayya… - 2022 - tdcommons.org
… Acetonitril (500,0 ml) werd toegevoegd aan 4-(1H-pyrazool-4-yl)-7-((2(trimethylsilyl)ethoxy)methyl){{8} }H-pyrrolo[2,3-d]pyrimidine
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